Protein shows reaction to breast cancer drug
The Irish Times, Health briefing by Claire O’Connell
MEASURING LEVELS of a particular protein in breast tumour tissue could ultimately help some early stage breast cancer patients avoid unnecessary drug treatment, according to new research.
The study centres on a protein called the cocaine- and amphetamine- regulated transcript, or Cart for short. By analysing samples from about 1,000 breast cancer patients, the international study, published online in the journal Oncogene, found levels of Cart are high in breast tumours that respond poorly to tamoxifen, one of the main anti-hormone drugs used to treat the disease.
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